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Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine

Received: 24 November 2020     Accepted: 29 December 2020     Published: 12 March 2021
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Abstract

There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis.

Published in American Journal of Laboratory Medicine (Volume 6, Issue 1)
DOI 10.11648/j.ajlm.20210601.12
Page(s) 8-16
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Biochemical Parameters, Hematological Profile, CRF, Martyr Mohammed El-Najjar Hospital, Rafah, Gaza Strip, Palestine

References
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Cite This Article
  • APA Style

    Mohamad Alhamss, Ahmad Tabash, Abdrabbou Elregeb, Ayman Abu Mustafa, Asmaa Hejazi, et al. (2021). Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine. American Journal of Laboratory Medicine, 6(1), 8-16. https://doi.org/10.11648/j.ajlm.20210601.12

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    ACS Style

    Mohamad Alhamss; Ahmad Tabash; Abdrabbou Elregeb; Ayman Abu Mustafa; Asmaa Hejazi, et al. Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine. Am. J. Lab. Med. 2021, 6(1), 8-16. doi: 10.11648/j.ajlm.20210601.12

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    AMA Style

    Mohamad Alhamss, Ahmad Tabash, Abdrabbou Elregeb, Ayman Abu Mustafa, Asmaa Hejazi, et al. Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine. Am J Lab Med. 2021;6(1):8-16. doi: 10.11648/j.ajlm.20210601.12

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  • @article{10.11648/j.ajlm.20210601.12,
      author = {Mohamad Alhamss and Ahmad Tabash and Abdrabbou Elregeb and Ayman Abu Mustafa and Asmaa Hejazi and Riyad Shaban and Ramy Sarafandi and Yaser Elarja and Nedal Hasanain and Shawgy Elhessy and Faten Allyan},
      title = {Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine},
      journal = {American Journal of Laboratory Medicine},
      volume = {6},
      number = {1},
      pages = {8-16},
      doi = {10.11648/j.ajlm.20210601.12},
      url = {https://doi.org/10.11648/j.ajlm.20210601.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20210601.12},
      abstract = {There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine
    AU  - Mohamad Alhamss
    AU  - Ahmad Tabash
    AU  - Abdrabbou Elregeb
    AU  - Ayman Abu Mustafa
    AU  - Asmaa Hejazi
    AU  - Riyad Shaban
    AU  - Ramy Sarafandi
    AU  - Yaser Elarja
    AU  - Nedal Hasanain
    AU  - Shawgy Elhessy
    AU  - Faten Allyan
    Y1  - 2021/03/12
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ajlm.20210601.12
    DO  - 10.11648/j.ajlm.20210601.12
    T2  - American Journal of Laboratory Medicine
    JF  - American Journal of Laboratory Medicine
    JO  - American Journal of Laboratory Medicine
    SP  - 8
    EP  - 16
    PB  - Science Publishing Group
    SN  - 2575-386X
    UR  - https://doi.org/10.11648/j.ajlm.20210601.12
    AB  - There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • Palestine College of Nursing, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • El Najar Hospital, Ministry of Health, Gaza Strip, Palestine

  • Department of Biochemistry, College of Medical Sciences, Israa University, Gaza, Palestine

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